Posttransplant lymphoproliferative disorders.
نویسندگان
چکیده
Posttransplant lymphoproliferative disorder is a heterogeneous group of clonal hyperplasia/neoplasms that can range from benign to highly malignant lesions. Mortality rates can approach 60%. This entity has been on the rise for the last 2 decades with the advent of highly potent immunosuppressive agents. Epstein-Barr virus has shown to play a primary role in more than 90% of the cases. Although standard protocols do not exist for primary prevention and treatment, new agents are emerging that may play a role in treatment and prevention of this debilitating, and at times, fatal disease.
منابع مشابه
Hepatitis C virus infection can affect lymphoproliferative disorders only as a cofactor for Epstein-Barr virus in liver transplant recipients: PTLD.Int survey.
OBJECTIVES Hepatitis C virus infection has a 10.5% frequency in liver transplant posttransplant lymphoproliferative disorders. Studies have suggested that hepatitis C virus infection plays a role in developing posttransplant lymphoproliferative disorders. Pooling data of posttransplant lymphoproliferative disorders developing in liver recipients from the literature, we analyzed and compared cha...
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WE HAVE PREVIOUSLY estimated a 20% frcquency of Epstein-Barr virus (EBV) related posttransplant lymphoproliferative disorders (PTLD) in small bowel allograft recipients. I The present study compares rates of PTLD among pediatric and adult recipients of isolated or composite small bowel allografts. We also report PTLD frequency before and after the institution of quantitative EBV monitoring and ...
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عنوان ژورنال:
- Iranian journal of kidney diseases
دوره 2 2 شماره
صفحات -
تاریخ انتشار 2008